STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapHChloramphenicol acetyltransferase. (202 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.905
yvfE
Cell wall biosynthesis regulatory pyridoxal phosphate-dependent protein; Belongs to the DegT/DnrJ/EryC1 family.
 
     0.876
neuC
N-acylglucosamine 2-epimerase.
 
     0.844
spsE_2
N-acetylneuraminic acid synthetase.
 
     0.831
neuA_1
CMP-N-acetlyneuraminic acid synthetase.
 
     0.817
Lqua_1983
LPS biosynthesis protein, PseA-like protein.
 
     0.788
hisH_1
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
    0.786
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.780
hisF_2
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.757
kpsM
Polysaccharide ABC transporter, permease protein.
       0.757
Your Current Organism:
Legionella quateirensis
NCBI taxonomy Id: 45072
Other names: ATCC 49507, CCUG 44899, CIP 105271, L. quateirensis, NCTC 12376
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