STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
ubiA4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (280 aa)    
Predicted Functional Partners:
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.896
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.896
Lsan_1052
acyl-CoA synthetase.
  
 0.880
pta
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.837
Lsan_2939
Phosphate acetyl/butaryl transferase.
  
 
 0.837
Lsan_1114
acyl-CoA synthetase.
  
 
 0.818
Lsan_2222
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.813
ubiC
4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
    
  0.799
rkpA
Type I polyketide synthase WcbR.
  
 0.787
Lsan_2556
Non-ribosomal peptide synthetase/polyketide synthetase.
  
 0.781
Your Current Organism:
Legionella santicrucis
NCBI taxonomy Id: 45074
Other names: ATCC 35301, CCUG 29673, CIP 103849, DSM 23075, JCM 7557, L. santicrucis, Legionella sancticrucis, Legionella santacruxensis, NCTC 11989, strain SC-63-C7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.