STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lsan_3199Putative iron-sulpher cluster proteins NifU. (126 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase.
  
 0.998
sufS
Selenocysteine lyase, PLP-dependent; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 0.966
djlA
Molecular chaperone DnaJ; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
 
 0.966
Lsan_2247
Aminotransferase class V.
  
 0.966
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.900
Lsan_1559
Oxidoreductase, FAD-binding protein.
  
 0.865
Lsan_0158
Xylene monooxygenase.
  
 0.864
sufA
Fe-S cluster assembly protein; Belongs to the HesB/IscA family.
  
  
 0.846
sufC
Component of SufBCD complex, ATP-binding component of ABC superfamily.
  
 
 0.838
Lsan_2927
Abi-like protein.
  
 0.834
Your Current Organism:
Legionella santicrucis
NCBI taxonomy Id: 45074
Other names: ATCC 35301, CCUG 29673, CIP 103849, DSM 23075, JCM 7557, L. santicrucis, Legionella sancticrucis, Legionella santacruxensis, NCTC 11989, strain SC-63-C7
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