close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lwor_0149Multidrug resistance ABC transporter ATP-binding protein. (593 aa)    
Predicted Functional Partners:
pksJ
Polyketide synthase, type I.
   
 0.945
Lwor_0641
Toxin secretion ATP binding protein.
 
 
 
0.831
Lwor_0209
Toxin secretion ABC transporter ATP-binding protein.
   
  0.821
Lwor_0289
Polyketide synthase; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.795
Lwor_0509
Peptide synthetase, non-ribosomal.
  
 
 0.734
Lwor_0212
Deoxyribodipyrimidine photolyase phrB; Belongs to the DNA photolyase family.
    
   0.700
Lwor_1229
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
   0.683
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
    
   0.683
ybeY
Metal dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
    
   0.683
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.670
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.