cbpA_2 protein (Legionella worsleiensis) - STRING interaction network

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Score

cbpA_2

Curved DNA binding protein DnaJ. (521 aa)

Predicted Functional Partners:

dnaK

0.990

Lwor_0263

0.969

grpE

0.965

Lwor_0291

0.927

htpG

0.927

htpB

0.850

rplM

0.839

rplC

0.831

queF

0.824

queF-2

0.824

Your Current Organism:

Legionella worsleiensis

NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lwor_0263	cbpA_2	Lwor_0263	Lwor_0195	Putative chaperone-modulator protein CbpM.	Curved DNA binding protein DnaJ.	0.969
Lwor_0291	cbpA_2	Lwor_0291	Lwor_0195	DNA mismatch repair protein.	Curved DNA binding protein DnaJ.	0.927
Lwor_0291	dnaK	Lwor_0291	Lwor_0796	DNA mismatch repair protein.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.997
Lwor_0291	grpE	Lwor_0291	Lwor_0795	DNA mismatch repair protein.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.881
Lwor_0291	htpB	Lwor_0291	Lwor_0026	DNA mismatch repair protein.	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.964
cbpA_2	Lwor_0263	Lwor_0195	Lwor_0263	Curved DNA binding protein DnaJ.	Putative chaperone-modulator protein CbpM.	0.969
cbpA_2	Lwor_0291	Lwor_0195	Lwor_0291	Curved DNA binding protein DnaJ.	DNA mismatch repair protein.	0.927
cbpA_2	dnaK	Lwor_0195	Lwor_0796	Curved DNA binding protein DnaJ.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.990
cbpA_2	grpE	Lwor_0195	Lwor_0795	Curved DNA binding protein DnaJ.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.965
cbpA_2	htpB	Lwor_0195	Lwor_0026	Curved DNA binding protein DnaJ.	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.850
cbpA_2	htpG	Lwor_0195	Lwor_0360	Curved DNA binding protein DnaJ.	Heat shock protein 90; Molecular chaperone. Has ATPase activity.	0.927
cbpA_2	queF	Lwor_0195	Lwor_0105	Curved DNA binding protein DnaJ.	GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.824
cbpA_2	queF-2	Lwor_0195	Lwor_1579	Curved DNA binding protein DnaJ.	GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.824
cbpA_2	rplC	Lwor_0195	Lwor_1438	Curved DNA binding protein DnaJ.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.831
cbpA_2	rplM	Lwor_0195	Lwor_1493	Curved DNA binding protein DnaJ.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.839
dnaK	Lwor_0291	Lwor_0796	Lwor_0291	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	DNA mismatch repair protein.	0.997
dnaK	cbpA_2	Lwor_0796	Lwor_0195	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Curved DNA binding protein DnaJ.	0.990
dnaK	grpE	Lwor_0796	Lwor_0795	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.999
dnaK	htpB	Lwor_0796	Lwor_0026	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.994
dnaK	htpG	Lwor_0796	Lwor_0360	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat shock protein 90; Molecular chaperone. Has ATPase activity.	0.998