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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lwor_0446Two component response regulator. (341 aa)    
Predicted Functional Partners:
Lwor_0281
Sensory histidine-kinase / response regulator.
  
 0.998
Lwor_0290
Sensory box histidine kinase/response regulator.
  
 0.998
Lwor_1015
Sensory histidine-kinase / response regulator.
  
 0.998
gacS/letS
Transmission sensor LetS.
 
 0.991
Lwor_1937
Sensory box protein.
  
 0.957
Lwor_0444
Sensor protein LuxN.
 
  0.941
Lwor_1687
Regulatory protein (GGDEF and EAL domains).
  
 0.939
Lwor_1947
Inner membrane protein.
  
 0.939
Lwor_2319
Chemotaxis signal transducer.
  
 0.929
Lwor_1174
Response regulator.
   
 0.896
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
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