Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lwor_0617Glutamate synthase; Belongs to the glutamate synthase family. (523 aa)    
Predicted Functional Partners:
fadH
2,4-dienoyl-CoA reductase FadH1.
  
 0.997
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.960
Lwor_0937
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.894
pksJ
Polyketide synthase, type I.
     
 0.855
Lwor_1464
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.842
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.826
zapA
Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
       0.794
Lwor_0615
Hypothetical protein; Belongs to the UPF0149 family.
       0.716
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.702
ubiH_2
2-octaprenyl-6-methoxyphenol hydroxylase.
       0.671
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
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