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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pipProline iminopeptidase; Belongs to the peptidase S33 family. (319 aa)    
Predicted Functional Partners:
Lwor_0509
Peptide synthetase, non-ribosomal.
   
 0.905
pksJ
Polyketide synthase, type I.
  
 0.888
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
   
  0.869
Lwor_2197
Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.852
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
  
    0.810
acpP_2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
  0.787
mhpC_1
Lipolytic enzyme.
  
  
  0.769
pta
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
    
 0.763
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  0.726
Lwor_1854
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
    
 0.712
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
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