Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
add_1Adenosine deaminase. (491 aa)    
Predicted Functional Partners:
xapA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.945
add_2
Adenosine deaminase.
  
  
  0.887
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.869
yfiH
Laccase domain protein YfiH; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.865
Lwor_1520
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.757
ctpA
Carboxy-terminal protease; Belongs to the peptidase S41A family.
   
   0.571
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.563
ppt
Hypoxanthine-guanine phosphoribosyltransferase.
     
 0.541
Lwor_0703
3'-nucleotidase/nuclease.
  
  
  0.513
Lwor_1513
DotA.
  
     0.453
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
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