typA protein (Legionella worsleiensis) - STRING interaction network

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[Homology]

Score

typA

Virulence regulator BipA. (608 aa)

Predicted Functional Partners:

recN

0.895

ppnK

0.876

guaA

0.842

rpsI

0.749

rpmI

0.727

tig

0.724

rplA

0.719

rpoB

0.696

tsf

0.658

infC

0.639

Your Current Organism:

Legionella worsleiensis

NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
guaA	infC	Lwor_2239	Lwor_1486	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; Belongs to the IF-3 family.	0.607
guaA	rplA	Lwor_2239	Lwor_1593	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.954
guaA	rpmI	Lwor_2239	Lwor_1487	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.553
guaA	rpoB	Lwor_2239	Lwor_1590	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.941
guaA	rpsI	Lwor_2239	Lwor_1494	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.755
guaA	tig	Lwor_2239	Lwor_1972	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.787
guaA	tsf	Lwor_2239	Lwor_2230	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.772
guaA	typA	Lwor_2239	Lwor_1368	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Virulence regulator BipA.	0.842
infC	guaA	Lwor_1486	Lwor_2239	Translation initiation factor IF-3; Belongs to the IF-3 family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.607
infC	rplA	Lwor_1486	Lwor_1593	Translation initiation factor IF-3; Belongs to the IF-3 family.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.946
infC	rpmI	Lwor_1486	Lwor_1487	Translation initiation factor IF-3; Belongs to the IF-3 family.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.994
infC	rpoB	Lwor_1486	Lwor_1590	Translation initiation factor IF-3; Belongs to the IF-3 family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.750
infC	rpsI	Lwor_1486	Lwor_1494	Translation initiation factor IF-3; Belongs to the IF-3 family.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.971
infC	tig	Lwor_1486	Lwor_1972	Translation initiation factor IF-3; Belongs to the IF-3 family.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.790
infC	tsf	Lwor_1486	Lwor_2230	Translation initiation factor IF-3; Belongs to the IF-3 family.	Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.943
infC	typA	Lwor_1486	Lwor_1368	Translation initiation factor IF-3; Belongs to the IF-3 family.	Virulence regulator BipA.	0.639
ppnK	recN	Lwor_1367	Lwor_1366	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	0.900
ppnK	typA	Lwor_1367	Lwor_1368	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Virulence regulator BipA.	0.876
recN	ppnK	Lwor_1366	Lwor_1367	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.900
recN	rpoB	Lwor_1366	Lwor_1590	DNA repair protein recN; May be involved in recombinational repair of damaged DNA.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.458