Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lwor_1668Glycosyltransferase, group 2 family protein (glycan biosynthesis). (333 aa)    
Predicted Functional Partners:
Lwor_2366
Melitin resistance protein.
 
 
 0.951
Lwor_1667
GtrA-like protein.
 
 
 0.938
Lwor_0509
Peptide synthetase, non-ribosomal.
  
 
 0.884
Lwor_2160
Aminotransferase WecE; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.675
yvfE
Cell wall biosynthesis regulatory pyridoxal phosphate-dependent protein; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.675
Lwor_1666
Cellobiose phosphorylase.
 
  
 0.643
fmt
Methionyl tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
 
 0.609
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
       0.585
hypB
Hydrogenase nickel incorporation protein HypB.
       0.585
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
       0.584
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
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