close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lwor_2012RasGEF domain protein. (984 aa)    
Predicted Functional Partners:
Lwor_2135
SET domain protein.
  
 
  0.908
Lwor_1874
Thaumatin domain-containing protein.
  
 
  0.870
flgB_2
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
     0.846
pksJ
Polyketide synthase, type I.
    
 0.822
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.792
Lwor_2466
Leucine Rich repeats (2 copies).
  
     0.770
rhsA
Putative deoxyribonuclease RhsA.
  
    0.769
Lwor_0866
Hypothetical protein.
  
     0.769
Lwor_2465
AAA domain (dynein-related subfamily).
  
     0.768
Lwor_0242
Ninein.
  
     0.766
Your Current Organism:
Legionella worsleiensis
NCBI taxonomy Id: 45076
Other names: ATCC 49508, CCUG 44923, CIP 105114, DSM 21907, L. worsleiensis, NCTC 12377
Server load: medium (42%) [HD]