Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
frmCS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa)    
Predicted Functional Partners:
adhI
S-(hydroxymethyl)glutathione dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
ARG96427.1
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
   
 
 0.911
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.732
ARG96794.1
Diadenosine tetraphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.725
ARG97776.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.634
hisC-2
Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
      0.612
ARG98277.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.481
ARG98330.1
Hybrid non-ribosomal peptide synthetase/type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.454
ARG97701.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.415
Your Current Organism:
Tatlockia micdadei
NCBI taxonomy Id: 451
Other names: ATCC 33218, CCUG 11882, CIP 103882, DSM 16640, Legionella micdadei, Legionella pittsburghensis, NCTC 11371, T. micdadei, strain TATLOCK
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