Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARG96980.1dGTPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dGTPase family. Type 2 subfamily. (440 aa)    
Predicted Functional Partners:
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.910
xapA
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.901
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.901
ARG96981.1
SPOR domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.573
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.515
lspM
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.502
ARG96257.1
Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.473
ARG98891.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.413
ARG96983.1
Hypothetical protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.412
Your Current Organism:
Tatlockia micdadei
NCBI taxonomy Id: 451
Other names: ATCC 33218, CCUG 11882, CIP 103882, DSM 16640, Legionella micdadei, Legionella pittsburghensis, NCTC 11371, T. micdadei, strain TATLOCK
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