STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARG98615.1P-type DNA transfer ATPase VirB11; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)    
Predicted Functional Partners:
ARG98616.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.986
ARG98613.1
P-type conjugative transfer protein VirB9; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.973
ARG98614.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.939
ARG98608.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.935
ARG98611.1
Legionella vir-like protein LvhB6; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.908
ARG98610.1
Protein LvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.800
ARG98612.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.800
ARG98617.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.778
ARG98609.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.637
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      0.636
Your Current Organism:
Tatlockia micdadei
NCBI taxonomy Id: 451
Other names: ATCC 33218, CCUG 11882, CIP 103882, DSM 16640, Legionella micdadei, Legionella pittsburghensis, NCTC 11371, T. micdadei, strain TATLOCK
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.