STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARG98628.1Site-specific integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)    
Predicted Functional Partners:
ARG98627.1
Excisionase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.780
ARG98626.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
ARG98833.1
Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.669
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.483
ARG96359.1
Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.477
ARG98941.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.475
ARG97931.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.444
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.417
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.402
Your Current Organism:
Tatlockia micdadei
NCBI taxonomy Id: 451
Other names: ATCC 33218, CCUG 11882, CIP 103882, DSM 16640, Legionella micdadei, Legionella pittsburghensis, NCTC 11371, T. micdadei, strain TATLOCK
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