Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lspi_0140Protein IcmE (DotG). (1080 aa)    
Predicted Functional Partners:
Lspi_0139
IcmK protein.
 
 
 
 0.991
Lspi_0141
Protein IcmG (DotF).
   
 
 0.971
dotC
Defect in organelle trafficking lipoprotein DotC.
  
 
 
 0.965
Lspi_0138
Protein IcmL (DotI).
 
   
 0.961
dotA
Defect in organelle trafficking protein DotA.
  
 
   0.958
lphA
LphA (DotK).
 
 
   0.893
Lspi_0136
Protein IcmL (DotI).
 
   
 0.888
Lspi_0134
Protein IcmO (DotL).
 
 
 
 0.867
Lspi_0681
Hypothetical protein.
 
 
 0.865
Lspi_0145
Protein IcmB (DotO).
 
 
 0.864
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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