Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lspi_0141Protein IcmG (DotF). (265 aa)    
Predicted Functional Partners:
Lspi_0140
Protein IcmE (DotG).
   
 
 0.971
Lspi_0139
IcmK protein.
   
 
 0.969
lphA
LphA (DotK).
   
   0.930
icmM/dotJ
Component of the Dot/Icm secretion system, predicted inner membrane protein.
     
 0.925
Lspi_0142
IcmC (DotE).
     
 0.872
Lspi_0138
Protein IcmL (DotI).
     
 0.860
icmD
Protein IcmD (DotP).
   
 
 0.843
dotC
Defect in organelle trafficking lipoprotein DotC.
    
 
 0.837
Lspi_0144
IcmJ protein.
     
 0.833
Lspi_1192
IcmX (IcmY).
    
 
 0.831
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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