Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lspi_0218RES domain protein. (243 aa)    
Predicted Functional Partners:
Lspi_0217
Hypothetical protein.
 
  
 0.987
Lspi_2699
Coiled-coil protein.
  
     0.623
Lspi_2724
Thaumatin domain-containing protein.
  
     0.574
Lspi_1595
Potassium efflux system KefA.
  
     0.530
Lspi_2682
Hypothetical protein.
  
     0.522
chiA
Chitinase A precursor.
  
     0.484
plaB
Phospholipase.
  
     0.481
bcp
Acetylpolyamine aminohydrolase.
  
     0.478
Lspi_0929
Tyrosine phosphatase II superfamily protein.
  
     0.405
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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