Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Lspi_0328Lipase A. (283 aa)    
Predicted Functional Partners:
Lspi_0327
Endonuclease/exonuclease/phosphatase family protein.
       0.724
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
  0.551
acdA
Acyl CoA dehydrogenase.
    
  0.538
Lspi_0658
Glutaryl CoA dehydrogenase.
    
  0.538
Lspi_0762
acyl-CoA dehydrogenase.
    
  0.538
fadE
acyl-CoA dehydrogenase.
    
  0.538
Lspi_2376
Short chain-specific acyl CoA dehydrogenase.
    
  0.538
Lspi_2651
Acyl CoA dehydrogenase.
    
  0.538
Lspi_2313
Ankyrin repeat protein.
 
 
  0.526
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
   0.471
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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