| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lspi_0331 | Lspi_0334 | Lspi_0331 | Lspi_0334 | Oxaloacetate decarboxylase subunit alpha. | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
| Lspi_0331 | Lspi_0866 | Lspi_0331 | Lspi_0866 | Oxaloacetate decarboxylase subunit alpha. | Pyruvate carboxylase subunit A. | 0.999 |
| Lspi_0331 | Lspi_2656 | Lspi_0331 | Lspi_2656 | Oxaloacetate decarboxylase subunit alpha. | Acyl CoA carboxylase subunit alpha. | 0.999 |
| Lspi_0331 | accA | Lspi_0331 | Lspi_2251 | Oxaloacetate decarboxylase subunit alpha. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.983 |
| Lspi_0331 | accD | Lspi_0331 | Lspi_1646 | Oxaloacetate decarboxylase subunit alpha. | Acetyl CoA carboxylase carboxyltransferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.994 |
| Lspi_0331 | birA | Lspi_0331 | Lspi_2249 | Oxaloacetate decarboxylase subunit alpha. | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.963 |
| Lspi_0331 | fabD | Lspi_0331 | Lspi_1541 | Oxaloacetate decarboxylase subunit alpha. | Malonyl CoA-ACP transacylase. | 0.854 |
| Lspi_0331 | fabH_1 | Lspi_0331 | Lspi_0054 | Oxaloacetate decarboxylase subunit alpha. | 3-oxoacyl-ACP synthase; Belongs to the thiolase-like superfamily. FabH family. | 0.887 |
| Lspi_0331 | fabH_2 | Lspi_0331 | Lspi_1540 | Oxaloacetate decarboxylase subunit alpha. | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.887 |
| Lspi_0331 | fabH_3 | Lspi_0331 | Lspi_1956 | Oxaloacetate decarboxylase subunit alpha. | 3-oxoacyl-ACP synthase. | 0.887 |
| Lspi_0334 | Lspi_0331 | Lspi_0334 | Lspi_0331 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Oxaloacetate decarboxylase subunit alpha. | 0.999 |
| Lspi_0334 | Lspi_0866 | Lspi_0334 | Lspi_0866 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Pyruvate carboxylase subunit A. | 0.556 |
| Lspi_0334 | Lspi_2656 | Lspi_0334 | Lspi_2656 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acyl CoA carboxylase subunit alpha. | 0.553 |
| Lspi_0334 | accA | Lspi_0334 | Lspi_2251 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.941 |
| Lspi_0334 | accD | Lspi_0334 | Lspi_1646 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl CoA carboxylase carboxyltransferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.989 |
| Lspi_0334 | birA | Lspi_0334 | Lspi_2249 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.969 |
| Lspi_0334 | fabD | Lspi_0334 | Lspi_1541 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Malonyl CoA-ACP transacylase. | 0.782 |
| Lspi_0334 | fabH_1 | Lspi_0334 | Lspi_0054 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-oxoacyl-ACP synthase; Belongs to the thiolase-like superfamily. FabH family. | 0.527 |
| Lspi_0334 | fabH_2 | Lspi_0334 | Lspi_1540 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.629 |
| Lspi_0334 | fabH_3 | Lspi_0334 | Lspi_1956 | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-oxoacyl-ACP synthase. | 0.456 |
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