Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lspi_0488Sensor kinase HydH. (333 aa)    
Predicted Functional Partners:
Lspi_0489
Sigma 54-dependent response regulator.
 0.996
fliE
Flagellar hook-basal body complex protein.
 
 
 
 0.844
gacS/letS
Transmission sensor LetS.
 
 
0.816
Lspi_0570
Guanylate cyclase.
  
 
 0.782
Lspi_0657
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
   
  0.766
fliG
Flagellar motor switch protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.726
fliF
Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
    0.707
Lspi_0179
Sensor histidine kinase.
 
 
0.652
fleQ
Transcriptional regulator FleQ.
 
 
 0.652
Lspi_0740
Sensory box histidine kinase.
 
 
 
 0.650
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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