Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trmJRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (247 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase NifS.
     
 0.857
sufA
Fe-S cluster assembly protein; Belongs to the HesB/IscA family.
  
    0.852
Lspi_0506
Putative iron-sulpher cluster proteins NifU.
       0.851
suhB_1
Inositol-1-monophosphatase.
 
    0.779
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     0.673
yjbN
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
   
 0.657
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
   
  
 0.601
Lspi_2581
Bifunctional pyrazinamidase/nicotinamidase.
 
      0.556
rlmE
Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
   
 0.552
rlmB
tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
      
 0.513
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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