fis_1 protein (Legionella spiritensis) - STRING interaction network

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fis_1

Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family. (94 aa)

Predicted Functional Partners:

Lspi_0037

0.706

polA

0.465

Lspi_0131

0.463

rnpA

0.427

Lspi_2854

0.402

Your Current Organism:

Legionella spiritensis

NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lspi_0037	fis_1	Lspi_0037	Lspi_0508	Nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	0.706
Lspi_0037	polA	Lspi_0037	Lspi_2109	Nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.503
Lspi_0037	rnpA	Lspi_0037	Lspi_0276	Nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Ribonuclease P protein component (RNase P); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.769
Lspi_0131	Lspi_2854	Lspi_0131	Lspi_2854	Lipoprotein.	SCP-2 sterol transfer family protein.	0.739
Lspi_0131	fis_1	Lspi_0131	Lspi_0508	Lipoprotein.	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	0.463
Lspi_2854	Lspi_0131	Lspi_2854	Lspi_0131	SCP-2 sterol transfer family protein.	Lipoprotein.	0.739
Lspi_2854	fis_1	Lspi_2854	Lspi_0508	SCP-2 sterol transfer family protein.	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	0.402
fis_1	Lspi_0037	Lspi_0508	Lspi_0037	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	Nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.706
fis_1	Lspi_0131	Lspi_0508	Lspi_0131	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	Lipoprotein.	0.463
fis_1	Lspi_2854	Lspi_0508	Lspi_2854	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	SCP-2 sterol transfer family protein.	0.402
fis_1	polA	Lspi_0508	Lspi_2109	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.465
fis_1	rnpA	Lspi_0508	Lspi_0276	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	Ribonuclease P protein component (RNase P); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.427
polA	Lspi_0037	Lspi_2109	Lspi_0037	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.503
polA	fis_1	Lspi_2109	Lspi_0508	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	0.465
polA	rnpA	Lspi_2109	Lspi_0276	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Ribonuclease P protein component (RNase P); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.686
rnpA	Lspi_0037	Lspi_0276	Lspi_0037	Ribonuclease P protein component (RNase P); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	Nitrogen regulation protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.769
rnpA	fis_1	Lspi_0276	Lspi_0508	Ribonuclease P protein component (RNase P); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	0.427
rnpA	polA	Lspi_0276	Lspi_2109	Ribonuclease P protein component (RNase P); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.686