Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lspi_0656Flagellar hook-length control protein FliK. (392 aa)    
Predicted Functional Partners:
Lspi_1390
Muramidase, peptidoglycan hydrolase FlgJ.
 
  
 0.983
flhB
Flagellar protein FlhB.
  
  
 0.898
fliH
Polar flagellar assembly protein FliH.
 
  
 0.885
flgD
Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
 
 
 0.867
Lspi_1013
Regulatory protein (GGDEF domain).
  
  
 0.860
Lspi_2448
Sensory box protein/GGDEF domain/EAL domain protein.
  
  
 0.860
flgK
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
 
  
 0.850
fliO
Flagellar protein fliO.
 
  
 0.842
Lspi_0382
Flagellar protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.839
flgH
Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
  
 0.831
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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