STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilSSensor protein PilS. (529 aa)    
Predicted Functional Partners:
pilR
Two component response regulator PilR.
 
 0.977
Lspi_0740
Sensory box histidine kinase.
 
 
0.958
gacS/letS
Transmission sensor LetS.
  
 0.942
Lspi_0570
Guanylate cyclase.
  
 0.942
Lspi_0179
Sensor histidine kinase.
 
 0.928
Lspi_0713
Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.891
Lspi_1013
Regulatory protein (GGDEF domain).
  
 0.863
Lspi_2448
Sensory box protein/GGDEF domain/EAL domain protein.
  
 0.863
Lspi_0181
GGDEF domain-containing sensory box protein.
  
 0.842
Lspi_1270
Diguanylate kinase.
  
 0.835
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.