Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Lspi_1012Two-component sensor histidine kinase. (475 aa)    
Predicted Functional Partners:
Lspi_1013
Regulatory protein (GGDEF domain).
 
 
 
 0.961
gacS/letS
Transmission sensor LetS.
 
 
 0.854
flgD
Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.845
Lspi_1011
FIST N domain protein.
 
   
 0.835
Lspi_2448
Sensory box protein/GGDEF domain/EAL domain protein.
 
 
 
 0.811
Lspi_0570
Guanylate cyclase.
  
 
 0.770
Lspi_1014
Hypothetical protein.
       0.757
Lspi_0181
GGDEF domain-containing sensory box protein.
 
 
 
 0.756
Lspi_0179
Sensor histidine kinase.
 
 
 
0.718
Lspi_2446
Regulatory protein (GGDEF, PAS, PAC domains).
 
 
 
 0.676
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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