Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lvrB3Legionella vir region protein. (102 aa)    
Predicted Functional Partners:
lvrA2_1
Vir region protein.
       0.736
csrA_1
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
       0.736
virB11
Conjugal transfer ATPase TrbB.
     
 0.677
trbE_1
Conjugal transfer protein TrbE.
       0.667
trbC_1
Conjugal transfer protein TrbC.
       0.666
Lspi_1235
Putative prophage repressor CI-like protein.
     
 0.657
trbI_1
Conjugal transfer protein TrbI.
       0.657
trbF_1
Conjugal transfer protein TrbF.
       0.654
Lspi_1245
Conjugal transfer protein TrbH.
       0.654
trbD_1
Conjugal transfer protein TrbD.
       0.648
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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