Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
comADNA uptake/competence protein ComA. (737 aa)    
Predicted Functional Partners:
comF
Competence protein ComF.
 
  
 0.938
smf
Protein smf.
 
  
 0.923
Lspi_2435
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.886
comEA
Competence protein ComEA.
  
  
 0.828
ftsK
Cell division protein FtsK.
 
  
 0.810
potA-2
Spermidine/putrescine ABC transporter, ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
     
 0.782
lspF
Type II secretory pathway protein LspF.
   
  
 0.780
pilC
Pilus assembly protein PilC.
   
  
 0.780
recX
Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family.
 
   
 0.773
Lspi_2215
Coiled-coil protein.
  
  
 0.768
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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