comA protein (Legionella spiritensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

comA

DNA uptake/competence protein ComA. (737 aa)

Predicted Functional Partners:

comF

0.907

smf

0.889

Lspi_2435

0.799

lspF

0.758

pilC

0.758

Lspi_2688

0.716

recX

0.667

Lspi_2215

0.662

holA

0.659

Lspi_1664

0.634

Your Current Organism:

Legionella spiritensis

NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lspi_1664	comA	Lspi_1664	Lspi_1663	Ectonucleoside triphosphate diphosphohydrolase I.	DNA uptake/competence protein ComA.	0.634
Lspi_2215	comA	Lspi_2215	Lspi_1663	Coiled-coil protein.	DNA uptake/competence protein ComA.	0.662
Lspi_2435	comA	Lspi_2435	Lspi_1663	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	DNA uptake/competence protein ComA.	0.799
Lspi_2435	lspF	Lspi_2435	Lspi_1619	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Type II secretory pathway protein LspF.	0.884
Lspi_2435	pilC	Lspi_2435	Lspi_2436	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Pilus assembly protein PilC.	0.959
Lspi_2435	smf	Lspi_2435	Lspi_0792	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Protein smf.	0.796
Lspi_2688	comA	Lspi_2688	Lspi_1663	Metal dependent phosphohydrolase.	DNA uptake/competence protein ComA.	0.716
Lspi_2688	comF	Lspi_2688	Lspi_0171	Metal dependent phosphohydrolase.	Competence protein ComF.	0.619
comA	Lspi_1664	Lspi_1663	Lspi_1664	DNA uptake/competence protein ComA.	Ectonucleoside triphosphate diphosphohydrolase I.	0.634
comA	Lspi_2215	Lspi_1663	Lspi_2215	DNA uptake/competence protein ComA.	Coiled-coil protein.	0.662
comA	Lspi_2435	Lspi_1663	Lspi_2435	DNA uptake/competence protein ComA.	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.799
comA	Lspi_2688	Lspi_1663	Lspi_2688	DNA uptake/competence protein ComA.	Metal dependent phosphohydrolase.	0.716
comA	comF	Lspi_1663	Lspi_0171	DNA uptake/competence protein ComA.	Competence protein ComF.	0.907
comA	holA	Lspi_1663	Lspi_1640	DNA uptake/competence protein ComA.	DNA polymerase III subunit delta.	0.659
comA	lspF	Lspi_1663	Lspi_1619	DNA uptake/competence protein ComA.	Type II secretory pathway protein LspF.	0.758
comA	pilC	Lspi_1663	Lspi_2436	DNA uptake/competence protein ComA.	Pilus assembly protein PilC.	0.758
comA	recX	Lspi_1663	Lspi_0465	DNA uptake/competence protein ComA.	Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family.	0.667
comA	smf	Lspi_1663	Lspi_0792	DNA uptake/competence protein ComA.	Protein smf.	0.889
comF	Lspi_2688	Lspi_0171	Lspi_2688	Competence protein ComF.	Metal dependent phosphohydrolase.	0.619
comF	comA	Lspi_0171	Lspi_1663	Competence protein ComF.	DNA uptake/competence protein ComA.	0.907