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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lspi_1908SAM-dependent O-methyltransferase. (229 aa)    
Predicted Functional Partners:
Lspi_0221
3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
   0.904
phaB_2
Acetyoacetyl CoA reductase.
 
  
   0.889
fabG_2
3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
   0.815
Lspi_2478
Hypothetical protein.
  
  
 0.800
phaB_1
Acetoacetyl CoA reductase.
 
  
   0.773
lly
4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.756
fabG_1
3-oxoacyl-ACP reductase.
 
  
   0.742
Lspi_1910
Glutathione S-transferase (maleylacetoacetate isomerase).
  
   0.722
Lspi_0944
Acetyoacetyl CoA reductase.
 
  
   0.699
pksJ_2
Polyketide synthase, type I.
   
 0.652
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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