Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thiJ4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme. (212 aa)    
Predicted Functional Partners:
Lspi_2012
Hypothetical protein.
       0.773
fosA
Glutathione transferase fosA (Fosfomycin resistance protein).
       0.773
Lspi_2014
Putative acetyltransferase.
       0.531
Lspi_2015
ATPase.
       0.531
Lspi_2016
Hypothetical protein.
       0.531
Lspi_2017
Aminoglycoside/hydroxyurea antibiotic resistance kinase.
       0.531
rpoD
RNA polymerase sigma 70 factor (RpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.492
phnA
Alkylphosphonate uptake protein PhnA.
       0.433
Lspi_2010
Hypothetical protein.
       0.408
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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