Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lspi_2017Aminoglycoside/hydroxyurea antibiotic resistance kinase. (310 aa)    
Predicted Functional Partners:
Lspi_2016
Hypothetical protein.
 
     0.880
Lspi_2014
Putative acetyltransferase.
 
     0.825
Lspi_2015
ATPase.
 
     0.813
Lspi_1985
Aminoglycoside phosphotransferase.
 
     0.760
fosA
Glutathione transferase fosA (Fosfomycin resistance protein).
 
     0.645
thiJ
4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme.
       0.531
Lspi_2012
Hypothetical protein.
       0.531
Lspi_2895
Helix-turn-helix domain protein.
  
     0.436
Lspi_1611
Putative Acetyltransferase, GNAT family.
  
     0.434
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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