Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lspi_2154Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (351 aa)    
Predicted Functional Partners:
Lspi_2155
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.995
Lspi_2410
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.971
Lspi_2615
Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.971
Lspi_1734
Integral membrane protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  0.970
lmxF
RND multidrug efflux transporter MexF.
  
  0.956
Lspi_2629
Outer membrane protein TolC.
 
 0.955
Lspi_2829
Outer membrane efflux protein.
  
  0.924
Lspi_2771
Outer membrane efflux lipoprotein.
   
  0.856
Lspi_1355
Outer membrane efflux protein.
   
  0.848
Lspi_0235
Agglutination protein.
  
 0.733
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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