Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hdaHHistone deacetylase-like amidohydrolase. (313 aa)    
Predicted Functional Partners:
yjeA
Endo-1,4-beta-xylanase-like protein.
    
  0.841
ppiB
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
  0.794
Lspi_1888
SNF2/RAD54 family transporter domain-containing protein.
    
 0.793
Lspi_1119
Protein phosphatase 2C.
   
   0.758
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
    
   0.758
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.716
htpG
Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.
    
 0.708
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.688
Lspi_1721
Oxidoreductase.
  
  0.657
atpD
ATP synthase F0F1 subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
 0.654
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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