Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa)    
Predicted Functional Partners:
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.949
Lspi_0331
Oxaloacetate decarboxylase subunit alpha.
  
 
 0.932
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 0.915
sfcA_1
Malate dehydrogenase.
   
 
 0.913
sfcA_2
Malate dehydrogenase.
   
 
 0.913
mao2
Malate oxidoreductase.
   
 
 0.913
Lspi_1029
2-oxoglutarate ferredoxin oxidoreductase beta subunit.
    
 0.913
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
     
 0.911
Lspi_2298
Pyruvate dehydrogenase E1 component oxidoreductase protein AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.909
Lspi_2345
Pyruvate decarboxylase.
     
 0.902
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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