Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lspi_2296Inner membrane protein AmpE. (250 aa)    
Predicted Functional Partners:
kefC_2
Sodium/hydrogen antiporter.
       0.853
Lspi_2297
Acyltransferase.
       0.782
Lspi_2298
Pyruvate dehydrogenase E1 component oxidoreductase protein AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.744
Lspi_2299
Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.681
iraA
Small-molecule methyltransferase IraA.
  
     0.666
Lspi_0088
Putative helicase/relaxase.
  
     0.649
Lspi_0313
Ankyrin repeat-containing protein.
  
     0.634
Lspi_2300
Dihydrolipoamide dehydrogenase.
       0.633
Lspi_0060
Coiled-coil protein.
  
     0.617
nadC
Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
     
 0.598
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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