Lspi_2371 protein (Legionella spiritensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

Lspi_2371

Cyclic nucleotide-binding protein. (265 aa)

Predicted Functional Partners:

Lspi_0713

0.886

Lspi_2331

0.827

Lspi_2588

0.790

Lspi_1917

0.783

Lspi_1354

0.779

Lspi_2373

0.774

proB

0.773

rpoD

0.772

rpoA

0.771

Lspi_1422

0.707

Your Current Organism:

Legionella spiritensis

NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lspi_0713	Lspi_1422	Lspi_0713	Lspi_1422	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Cyclic nucleotide-binding protein.	0.887
Lspi_0713	Lspi_1917	Lspi_0713	Lspi_1917	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate/guanylate cyclase transmembrane protein.	0.582
Lspi_0713	Lspi_2331	Lspi_0713	Lspi_2331	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	cNMP binding domain-containing protein.	0.861
Lspi_0713	Lspi_2371	Lspi_0713	Lspi_2371	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Cyclic nucleotide-binding protein.	0.886
Lspi_0713	Lspi_2588	Lspi_0713	Lspi_2588	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase.	0.785
Lspi_1354	Lspi_1422	Lspi_1354	Lspi_1422	Adenylate cyclase.	Cyclic nucleotide-binding protein.	0.812
Lspi_1354	Lspi_2331	Lspi_1354	Lspi_2331	Adenylate cyclase.	cNMP binding domain-containing protein.	0.792
Lspi_1354	Lspi_2371	Lspi_1354	Lspi_2371	Adenylate cyclase.	Cyclic nucleotide-binding protein.	0.779
Lspi_1422	Lspi_0713	Lspi_1422	Lspi_0713	Cyclic nucleotide-binding protein.	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.887
Lspi_1422	Lspi_1354	Lspi_1422	Lspi_1354	Cyclic nucleotide-binding protein.	Adenylate cyclase.	0.812
Lspi_1422	Lspi_1917	Lspi_1422	Lspi_1917	Cyclic nucleotide-binding protein.	Adenylate/guanylate cyclase transmembrane protein.	0.824
Lspi_1422	Lspi_2371	Lspi_1422	Lspi_2371	Cyclic nucleotide-binding protein.	Cyclic nucleotide-binding protein.	0.707
Lspi_1422	Lspi_2373	Lspi_1422	Lspi_2373	Cyclic nucleotide-binding protein.	Adenylate cyclase.	0.811
Lspi_1422	Lspi_2588	Lspi_1422	Lspi_2588	Cyclic nucleotide-binding protein.	Adenylate cyclase.	0.823
Lspi_1422	rpoA	Lspi_1422	Lspi_1790	Cyclic nucleotide-binding protein.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.771
Lspi_1422	rpoD	Lspi_1422	Lspi_0349	Cyclic nucleotide-binding protein.	RNA polymerase sigma 70 factor (RpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.772
Lspi_1917	Lspi_0713	Lspi_1917	Lspi_0713	Adenylate/guanylate cyclase transmembrane protein.	Guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.582
Lspi_1917	Lspi_1422	Lspi_1917	Lspi_1422	Adenylate/guanylate cyclase transmembrane protein.	Cyclic nucleotide-binding protein.	0.824
Lspi_1917	Lspi_2331	Lspi_1917	Lspi_2331	Adenylate/guanylate cyclase transmembrane protein.	cNMP binding domain-containing protein.	0.821
Lspi_1917	Lspi_2371	Lspi_1917	Lspi_2371	Adenylate/guanylate cyclase transmembrane protein.	Cyclic nucleotide-binding protein.	0.783