Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilBPilus assembly protein PilB. (574 aa)    
Predicted Functional Partners:
pilC
Pilus assembly protein PilC.
 
 
 0.998
lspF
Type II secretory pathway protein LspF.
 
 
 0.992
Lspi_2435
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.984
Lspi_0409
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
 
 0.901
pilZ_1
Type 4 fimbrial biogenesis protein PilZ.
  
 
 
 0.819
lspG
Type II secretory pathway protein LspG.
 
 
 0.797
pilM
Tfp pilus assembly protein, ATPase PilM.
 
 
 
 0.780
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
 
 
 0.770
Lspi_1621
General secretion pathway protein LspH.
  
 
 0.743
lspI
Type II secretory pathway protein LspI.
  
 
 0.743
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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