Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hipA_4HipA protein, DNA binding regulator. (411 aa)    
Predicted Functional Partners:
Lspi_2503
Transcriptional regulator.
 
  
 0.953
Lspi_1411
Transcriptional regulator.
 
    0.767
Lspi_2814
Transcriptional regulator.
 
    0.701
Lspi_2487
HipA protein.
 
 
 
0.686
Lspi_2488
Putative DNA-binding transcriptional regulator.
 
     0.628
Lspi_2516
Hypothetical protein; HipA-like C-terminal domain.
  
     0.554
Lspi_2285
Transcriptional regulator.
   
 
 0.553
Lspi_1992
Hypothetical protein.
  
    0.528
Lspi_2672
Putative DNA-binding transcriptional regulator.
 
    0.460
Lspi_1071
Filamentation induced by cAMP protein Fic.
  
     0.457
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
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