close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argHArgininosuccinate lyase. (418 aa)    
Predicted Functional Partners:
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.999
argF
Ornithine carbamoyltransferase.
 
  
 0.994
argD
Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.959
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.939
Lspi_2573
Amino acid (glutamine) ABC transporter ATP binding protein.
 
    0.851
Lspi_2572
Amino acid (glutamine) ABC transporter permease.
  
  
 0.844
yqiX
Amino acid (glutamine) ABC transporter periplasmic amino acid binding protein.
  
  
 0.797
lysAC
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.785
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  
 0.748
dlpA
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein).
  
 
 0.719
Your Current Organism:
Legionella spiritensis
NCBI taxonomy Id: 452
Other names: ATCC 35249, CCUG 29715, CCUG 31118, CIP 103850, DSM 19324, JCM 7562, L. spiritensis, NCTC 11990, strain Mount Saint Helens 9
Server load: low (20%) [HD]