TCAP_03625 protein (Tolypocladium capitatum)

Nodes:

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TCAP_03625

Respiratory supercomplex factor 2. (230 aa)

Predicted Functional Partners:

TCAP_01564

0.984

TCAP_04133

0.962

TCAP_07064

0.906

TCAP_04501

0.906

TCAP_05527

0.875

TCAP_06658

0.872

TCAP_05891

0.872

TCAP_00853

0.824

TCAP_07077

0.816

TCAP_03852

0.811

Your Current Organism:

Tolypocladium capitatum

NCBI taxonomy Id: 45235
Other names: Clavaria capitata, Cordyceps capitata, Elaphocordyceps capitata, T. capitatum, Tolypocladium capitatum (Holmsk. : Fr.) Quandt, Kepler & Spatafora, 2014, Torrubia capitata

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TCAP_00853	TCAP_01564	A0A2K3QNW5	A0A2K3QLU5	Cytochrome c oxidase subunit 6B-like protein.	Cytochrome c oxidase polypeptide VIb.	0.576
TCAP_00853	TCAP_03625	A0A2K3QNW5	A0A2K3QFY8	Cytochrome c oxidase subunit 6B-like protein.	Respiratory supercomplex factor 2.	0.824
TCAP_00853	TCAP_03852	A0A2K3QNW5	A0A2K3QF95	Cytochrome c oxidase subunit 6B-like protein.	Uncharacterized protein.	0.900
TCAP_00853	TCAP_04133	A0A2K3QNW5	A0A2K3QEG5	Cytochrome c oxidase subunit 6B-like protein.	Cytochrome b-c1 complex subunit 8.	0.993
TCAP_00853	TCAP_04501	A0A2K3QNW5	A0A2K3QDD9	Cytochrome c oxidase subunit 6B-like protein.	Cytochrome c oxidase subunit 6A, mitochondrial.	0.977
TCAP_00853	TCAP_05527	A0A2K3QNW5	A0A2K3QAG2	Cytochrome c oxidase subunit 6B-like protein.	Mitochondrial-processing peptidase subunit beta.	0.960
TCAP_00853	TCAP_05891	A0A2K3QNW5	A0A2K3Q9I5	Cytochrome c oxidase subunit 6B-like protein.	Cytochrome c oxidase subunit 4, mitochondrial.	0.978
TCAP_00853	TCAP_06658	A0A2K3QNW5	A0A2K3Q790	Cytochrome c oxidase subunit 6B-like protein.	Uncharacterized protein.	0.968
TCAP_00853	TCAP_07064	A0A2K3QNW5	A0A2K3Q5A6	Cytochrome c oxidase subunit 6B-like protein.	Cytochrome c oxidase subunit 6A, mitochondrial.	0.977
TCAP_00853	TCAP_07077	A0A2K3QNW5	A0A2K3Q518	Cytochrome c oxidase subunit 6B-like protein.	Cytochrome c1, heme protein, mitochondrial.	0.968
TCAP_01564	TCAP_00853	A0A2K3QLU5	A0A2K3QNW5	Cytochrome c oxidase polypeptide VIb.	Cytochrome c oxidase subunit 6B-like protein.	0.576
TCAP_01564	TCAP_03625	A0A2K3QLU5	A0A2K3QFY8	Cytochrome c oxidase polypeptide VIb.	Respiratory supercomplex factor 2.	0.984
TCAP_01564	TCAP_03852	A0A2K3QLU5	A0A2K3QF95	Cytochrome c oxidase polypeptide VIb.	Uncharacterized protein.	0.994
TCAP_01564	TCAP_04133	A0A2K3QLU5	A0A2K3QEG5	Cytochrome c oxidase polypeptide VIb.	Cytochrome b-c1 complex subunit 8.	0.998
TCAP_01564	TCAP_04501	A0A2K3QLU5	A0A2K3QDD9	Cytochrome c oxidase polypeptide VIb.	Cytochrome c oxidase subunit 6A, mitochondrial.	0.997
TCAP_01564	TCAP_05527	A0A2K3QLU5	A0A2K3QAG2	Cytochrome c oxidase polypeptide VIb.	Mitochondrial-processing peptidase subunit beta.	0.994
TCAP_01564	TCAP_05891	A0A2K3QLU5	A0A2K3Q9I5	Cytochrome c oxidase polypeptide VIb.	Cytochrome c oxidase subunit 4, mitochondrial.	0.998
TCAP_01564	TCAP_06658	A0A2K3QLU5	A0A2K3Q790	Cytochrome c oxidase polypeptide VIb.	Uncharacterized protein.	0.993
TCAP_01564	TCAP_07064	A0A2K3QLU5	A0A2K3Q5A6	Cytochrome c oxidase polypeptide VIb.	Cytochrome c oxidase subunit 6A, mitochondrial.	0.997
TCAP_01564	TCAP_07077	A0A2K3QLU5	A0A2K3Q518	Cytochrome c oxidase polypeptide VIb.	Cytochrome c1, heme protein, mitochondrial.	0.997

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

26

PPI enrichment p-value:

3.23e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006633

Fatty acid biosynthetic process

8 of 17

2.07

4.9

2.49e-12

GO:2001295

malonyl-CoA biosynthetic process

2 of 4

2.1

0.96

0.0159

GO:0044281

Small molecule metabolic process

9 of 458

0.69

0.58

0.00035

GO:0071704

Organic substance metabolic process

11 of 1212

0.36

0.29

0.0098

GO:0044238

Primary metabolic process

10 of 999

0.4

0.29

0.0198

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004312

Fatty acid synthase activity

4 of 7

2.16

2.31

2.74e-05

GO:0016747

Acyltransferase activity, transferring groups other than amino-acyl groups

5 of 41

1.48

1.52

0.00014

GO:0000036

Acyl carrier activity

2 of 2

2.4

1.02

0.0133

GO:0003989

acetyl-CoA carboxylase activity

2 of 3

2.22

1.01

0.0133

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 5

2.0

0.93

0.0169

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009317

acetyl-CoA carboxylase complex

2 of 4

2.1

1.07

0.0096

GO:0005737

Cytoplasm

11 of 997

0.44

0.36

0.0020

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1342

Fatty acid metabolism, and Alpha/beta hydrolase fold

7 of 13

2.13

4.56

6.41e-11

CL:1345

Fatty acid metabolism

4 of 8

2.1

2.57

5.86e-06

CL:1199

Mixed, incl. Pyruvate metabolism, and Citrate cycle (TCA cycle)

8 of 91

1.34

1.94

6.37e-08

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pace01212

Fatty acid metabolism

6 of 10

2.18

4.29

5.66e-10

pace00061

Fatty acid biosynthesis

6 of 10

2.18

4.29

5.66e-10

pace00780

Biotin metabolism

4 of 11

1.96

2.46

5.80e-06

pace01100

Metabolic pathways

9 of 530

0.63

0.53

0.00035

pace01110

Biosynthesis of secondary metabolites

5 of 249

0.7

0.42

0.0351

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

2 of 4

2.1

0.84

0.0276

GOCC:0005737

Cytoplasm

10 of 756

0.52

0.39

0.0054

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0275

Fatty acid biosynthesis

5 of 9

2.14

3.49

4.57e-08

KW-0444

Lipid biosynthesis

6 of 21

1.85

3.07

4.33e-08

KW-0596

Phosphopantetheine

2 of 2

2.4

1.33

0.0035

KW-0012

Acyltransferase

3 of 24

1.5

1.05

0.0044

KW-0963

Cytoplasm

6 of 253

0.77

0.56

0.0057

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01039

Carboxyl transferase domain

2 of 2

2.4

0.77

0.0390

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