STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCAP_00503Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (434 aa)    
Predicted Functional Partners:
TCAP_00645
Nitrogen assimilation transcription factor nit-4.
   
 0.993
TCAP_00748
Serine/threonine-protein kinase apg-1.
   
 
 0.971
TCAP_00051
Lipase atg15.
   
 
 0.963
TCAP_07073
Autophagy-related protein 3.
   
 
 0.779
TCAP_03617
Autophagy-like protein 18.
   
 
 0.758
TCAP_04654
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 
 0.706
TCAP_03216
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
   
 
 0.676
TCAP_03633
Vacuolar protein sorting-associated protein atg6.
    
 
 0.670
TCAP_07039
Multidomain presynaptic cytomatrix related protein.
   
 
 0.624
TCAP_00494
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.590
Your Current Organism:
Tolypocladium capitatum
NCBI taxonomy Id: 45235
Other names: Clavaria capitata, Cordyceps capitata, Elaphocordyceps capitata, T. capitatum, Tolypocladium capitatum (Holmsk. : Fr.) Quandt, Kepler & Spatafora, 2014, Torrubia capitata
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