| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMD84828.1 | AMD84845.1 | AXF12_04445 | AXF12_04540 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
| AMD84828.1 | AMD85296.1 | AXF12_04445 | AXF12_07095 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
| AMD84828.1 | AMD85316.1 | AXF12_04445 | AXF12_07220 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.483 |
| AMD84828.1 | AMD85317.1 | AXF12_04445 | AXF12_07225 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |
| AMD84828.1 | AMD85385.1 | AXF12_04445 | AXF12_07590 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.865 |
| AMD84828.1 | AMD85974.1 | AXF12_04445 | AXF12_10900 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
| AMD84828.1 | glyA | AXF12_04445 | AXF12_08100 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.591 |
| AMD84828.1 | thrB | AXF12_04445 | AXF12_08550 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.998 |
| AMD84828.1 | trpB | AXF12_04445 | AXF12_00275 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.532 |
| AMD84845.1 | AMD84828.1 | AXF12_04540 | AXF12_04445 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
| AMD84845.1 | AMD85296.1 | AXF12_04540 | AXF12_07095 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.862 |
| AMD84845.1 | AMD85316.1 | AXF12_04540 | AXF12_07220 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.834 |
| AMD84845.1 | AMD85317.1 | AXF12_04540 | AXF12_07225 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.961 |
| AMD84845.1 | AMD85385.1 | AXF12_04540 | AXF12_07590 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.912 |
| AMD84845.1 | AMD85974.1 | AXF12_04540 | AXF12_10900 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
| AMD84845.1 | cysS | AXF12_04540 | AXF12_07030 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.559 |
| AMD84845.1 | glyA | AXF12_04540 | AXF12_08100 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
| AMD84845.1 | thrB | AXF12_04540 | AXF12_08550 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.820 |
| AMD84845.1 | trpB | AXF12_04540 | AXF12_00275 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.901 |
| AMD85296.1 | AMD84828.1 | AXF12_07095 | AXF12_04445 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |