Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
Oter_0044Multi-sensor signal transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PAS fold-4 domain protein; KEGG: pol:Bpro_0708 periplasmic sensor signal transduction histidine kinase. (560 aa)    
Predicted Functional Partners:
Oter_1136
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: bra:BRADO3946 putative sensor histidine kinase with a GAF domain and multiple HAMP and response regulator receiver domains (modular protein).
  
 
 0.987
Oter_0776
KEGG: bra:BRADO5752 putative sensor histidine kinase with multiple PAS/PAC and a response regulator receiver domain; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; GAF domain protein.
  
 
 0.974
Oter_0043
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: sat:SYN_02588 response regulator with a HTH DNA-binding domain.
 
 
 0.968
Oter_2216
KEGG: cya:CYA_2836 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.960
Oter_1135
PAS/PAC sensor hybrid histidine kinase; KEGG: gvi:gll0634 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.952
Oter_1811
Multi-sensor hybrid histidine kinase; KEGG: rso:RS05068 probable composite two-component transcriptional regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.952
Oter_4246
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; Two component regulator three Y domain protein; KEGG: xcb:XC_1260 histidine kinase/response regulator hybrid protein.
  
 
 0.951
Oter_0038
Multi-sensor signal transduction histidine kinase; KEGG: scl:sce5100 two-component hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.941
Oter_0808
KEGG: bvi:Bcep1808_5667 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.941
Oter_0945
KEGG: ava:Ava_4753 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.941
Your Current Organism:
Opitutus terrae
NCBI taxonomy Id: 452637
Other names: O. terrae PB90-1, Opitutus terrae DSM 11246, Opitutus terrae PB90-1, Verrucomicrobiales PB90-1, Verrucomicrobiales str. PB90-1
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