STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oter_1156Excinuclease ABC C subunit domain protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (510 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.994
Oter_3168
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 
 0.850
Oter_4158
PFAM: UvrD/REP helicase; KEGG: sat:SYN_02537 UvrD/rep helicase.
 
  
 0.841
Oter_2709
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 
 0.788
Oter_1157
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: pth:PTH_1300 predicted nucleotide-utilizing enzyme; Belongs to the CinA family.
     
 0.751
Oter_1155
Sialate O-acetylesterase; PFAM: protein of unknown function DUF303 acetylesterase putative; KEGG: sus:Acid_3201 sialate O-acetylesterase.
       0.737
Oter_1629
DNA-formamidopyrimidine glycosylase; PFAM: zinc finger Fpg domain protein; Formamidopyrimidine-DNA glycosylase catalytic domain protein; Formamidopyrimidine-DNA glycolase, H2TH DNA binding; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.
  
  
 0.600
Oter_2372
PFAM: Formamidopyrimidine-DNA glycosylase catalytic domain protein; Formamidopyrimidine-DNA glycolase, H2TH DNA binding; KEGG: gsu:GSU0997 formamidopyrimidine-DNA glycosylase.
  
  
 0.600
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
 
  
 0.578
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
 
 
 0.538
Your Current Organism:
Opitutus terrae
NCBI taxonomy Id: 452637
Other names: O. terrae PB90-1, Opitutus terrae DSM 11246, Opitutus terrae PB90-1, Verrucomicrobiales PB90-1, Verrucomicrobiales str. PB90-1
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