STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Oter_1788PFAM: ATP-cone domain protein; KEGG: rrs:RoseRS_4577 ribonucleoside-triphosphate reductase. (842 aa)    
Predicted Functional Partners:
Oter_2126
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
   
 
 0.918
Oter_4565
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sat:SYN_01481 adenylate cyclase.
  
  
  0.914
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.900
Oter_0078
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; KEGG: bba:Bd1116 adenylate cyclase.
     
  0.900
Oter_0991
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: gur:Gura_0668 putative adenylate/guanylate cyclase.
     
  0.900
Oter_1561
KEGG: rba:RB10277 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
  0.900
Oter_2667
PFAM: nucleoside diphosphate kinase; KEGG: rba:RB11832 nucleoside diphosphate kinase (NDK); Belongs to the NDK family.
     
  0.900
Oter_3501
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: aba:Acid345_3884 adenylate/guanylate cyclase.
     
  0.900
Oter_3523
KEGG: spc:Sputcn32_0159 deoxyguanosinetriphosphate triphosphohydrolase-like protein; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily.
     
  0.900
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
Your Current Organism:
Opitutus terrae
NCBI taxonomy Id: 452637
Other names: O. terrae PB90-1, Opitutus terrae DSM 11246, Opitutus terrae PB90-1, Verrucomicrobiales PB90-1, Verrucomicrobiales str. PB90-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.