Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SETBP1SET binding protein 1. (1585 aa)    
Predicted Functional Partners:
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.784
ENSNVIP00000003657
PHD finger protein 6.
   
 0.647
KDM6A
Lysine demethylase 6A.
   
 0.599
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.594
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
     
 0.574
KDM6B
Lysine demethylase 6B.
   
 0.572
SH2B3
SH2B adaptor protein 3.
      
 0.567
CSF3R
Colony stimulating factor 3 receptor.
     
 0.564
KMT5A
Lysine methyltransferase 5A.
     
 0.564
ASXL1
ASXL transcriptional regulator 1.
    
 
 0.563
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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