SNCA protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Coexpression

Experiments

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[Homology]

Score

SNCA

Synuclein alpha. (140 aa)

Predicted Functional Partners:

SNCAIP

0.984

ENSNVIP00000003538

0.983

ENSNVIP00000013865

0.983

MAPT

0.983

SLC6A3

0.974

HSPA4

0.968

APP

0.964

SNCB

0.964

ENSNVIP00000009764

0.959

APOE

0.949

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOE	APP	ENSNVIP00000009643	ENSNVIP00000004429	Apolipoprotein E.	Amyloid beta precursor protein.	0.987
APOE	MAPT	ENSNVIP00000009643	ENSNVIP00000029972	Apolipoprotein E.	Microtubule associated protein tau.	0.960
APOE	SNCA	ENSNVIP00000009643	ENSNVIP00000000095	Apolipoprotein E.	Synuclein alpha.	0.949
APP	APOE	ENSNVIP00000004429	ENSNVIP00000009643	Amyloid beta precursor protein.	Apolipoprotein E.	0.987
APP	ENSNVIP00000003538	ENSNVIP00000004429	ENSNVIP00000003538	Amyloid beta precursor protein.	annotation not available	0.668
APP	ENSNVIP00000013865	ENSNVIP00000004429	ENSNVIP00000013865	Amyloid beta precursor protein.	annotation not available	0.668
APP	HSPA4	ENSNVIP00000004429	ENSNVIP00000022104	Amyloid beta precursor protein.	Heat shock protein family A (Hsp70) member 4.	0.516
APP	MAPT	ENSNVIP00000004429	ENSNVIP00000029972	Amyloid beta precursor protein.	Microtubule associated protein tau.	0.966
APP	SNCA	ENSNVIP00000004429	ENSNVIP00000000095	Amyloid beta precursor protein.	Synuclein alpha.	0.964
ENSNVIP00000003538	APP	ENSNVIP00000003538	ENSNVIP00000004429	annotation not available	Amyloid beta precursor protein.	0.668
ENSNVIP00000003538	ENSNVIP00000009764	ENSNVIP00000003538	ENSNVIP00000009764	annotation not available	annotation not available	0.538
ENSNVIP00000003538	ENSNVIP00000013865	ENSNVIP00000003538	ENSNVIP00000013865	annotation not available	annotation not available	0.923
ENSNVIP00000003538	HSPA4	ENSNVIP00000003538	ENSNVIP00000022104	annotation not available	Heat shock protein family A (Hsp70) member 4.	0.889
ENSNVIP00000003538	MAPT	ENSNVIP00000003538	ENSNVIP00000029972	annotation not available	Microtubule associated protein tau.	0.835
ENSNVIP00000003538	SLC6A3	ENSNVIP00000003538	ENSNVIP00000031686	annotation not available	Solute carrier family 6 member 3.	0.468
ENSNVIP00000003538	SNCA	ENSNVIP00000003538	ENSNVIP00000000095	annotation not available	Synuclein alpha.	0.983
ENSNVIP00000003538	SNCAIP	ENSNVIP00000003538	ENSNVIP00000026871	annotation not available	Synuclein alpha interacting protein.	0.980
ENSNVIP00000009764	ENSNVIP00000003538	ENSNVIP00000009764	ENSNVIP00000003538	annotation not available	annotation not available	0.538
ENSNVIP00000009764	ENSNVIP00000013865	ENSNVIP00000009764	ENSNVIP00000013865	annotation not available	annotation not available	0.538
ENSNVIP00000009764	SLC6A3	ENSNVIP00000009764	ENSNVIP00000031686	annotation not available	Solute carrier family 6 member 3.	0.757