GRHL2 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GRHL2

Grainyhead like transcription factor 2. (638 aa)

Predicted Functional Partners:

HOXB6

0.694

TRIP13

0.622

TAF2

0.621

LMO4

0.598

ESRP1

0.554

ESRP2

0.547

GLIS2

0.494

ENSNVIP00000008964

0.490

RNF2

0.490

ENSNVIP00000016705

0.490

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNVIP00000008964	ENSNVIP00000016705	ENSNVIP00000008964	ENSNVIP00000016705	annotation not available	annotation not available	0.542
ENSNVIP00000008964	GRHL2	ENSNVIP00000008964	ENSNVIP00000001012	annotation not available	Grainyhead like transcription factor 2.	0.490
ENSNVIP00000008964	RNF2	ENSNVIP00000008964	ENSNVIP00000012563	annotation not available	Ring finger protein 2.	0.997
ENSNVIP00000016705	ENSNVIP00000008964	ENSNVIP00000016705	ENSNVIP00000008964	annotation not available	annotation not available	0.542
ENSNVIP00000016705	GRHL2	ENSNVIP00000016705	ENSNVIP00000001012	annotation not available	Grainyhead like transcription factor 2.	0.490
ENSNVIP00000016705	RNF2	ENSNVIP00000016705	ENSNVIP00000012563	annotation not available	Ring finger protein 2.	0.997
ESRP1	ESRP2	ENSNVIP00000001808	ENSNVIP00000011272	Epithelial splicing regulatory protein 1.	Epithelial splicing regulatory protein 2.	0.881
ESRP1	GRHL2	ENSNVIP00000001808	ENSNVIP00000001012	Epithelial splicing regulatory protein 1.	Grainyhead like transcription factor 2.	0.554
ESRP2	ESRP1	ENSNVIP00000011272	ENSNVIP00000001808	Epithelial splicing regulatory protein 2.	Epithelial splicing regulatory protein 1.	0.881
ESRP2	GRHL2	ENSNVIP00000011272	ENSNVIP00000001012	Epithelial splicing regulatory protein 2.	Grainyhead like transcription factor 2.	0.547
GLIS2	GRHL2	ENSNVIP00000001046	ENSNVIP00000001012	GLIS family zinc finger 2.	Grainyhead like transcription factor 2.	0.494
GRHL2	ENSNVIP00000008964	ENSNVIP00000001012	ENSNVIP00000008964	Grainyhead like transcription factor 2.	annotation not available	0.490
GRHL2	ENSNVIP00000016705	ENSNVIP00000001012	ENSNVIP00000016705	Grainyhead like transcription factor 2.	annotation not available	0.490
GRHL2	ESRP1	ENSNVIP00000001012	ENSNVIP00000001808	Grainyhead like transcription factor 2.	Epithelial splicing regulatory protein 1.	0.554
GRHL2	ESRP2	ENSNVIP00000001012	ENSNVIP00000011272	Grainyhead like transcription factor 2.	Epithelial splicing regulatory protein 2.	0.547
GRHL2	GLIS2	ENSNVIP00000001012	ENSNVIP00000001046	Grainyhead like transcription factor 2.	GLIS family zinc finger 2.	0.494
GRHL2	HOXB6	ENSNVIP00000001012	ENSNVIP00000007617	Grainyhead like transcription factor 2.	Homeobox B6.	0.694
GRHL2	LMO4	ENSNVIP00000001012	ENSNVIP00000013046	Grainyhead like transcription factor 2.	LIM domain only 4.	0.598
GRHL2	RNF2	ENSNVIP00000001012	ENSNVIP00000012563	Grainyhead like transcription factor 2.	Ring finger protein 2.	0.490
GRHL2	TAF2	ENSNVIP00000001012	ENSNVIP00000008085	Grainyhead like transcription factor 2.	TATA-box binding protein associated factor 2.	0.621