Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH3BP2SH3 domain binding protein 2. (563 aa)    
Predicted Functional Partners:
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.989
PLCG1
Phospholipase C gamma 1.
    
 0.983
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.960
PLCG2
Phospholipase C gamma 2.
    
 0.960
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.958
SYK
Spleen associated tyrosine kinase.
    
 
 0.917
TNKS2
Tankyrase 2.
    
 
 0.886
ENSNVIP00000007493
Linker for activation of T cells.
    
 
 0.878
DBNL
Drebrin like.
    
 
 0.737
TNKS
Tankyrase.
    
 
 0.732
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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